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MEDICATION INTERACTIONS |
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by Zaneta M. Pronsky, MS, RD, FADA
New drug listings in the 11th edition:
Here is a listing of the new drugs added to the 11th edition. Many
other drug listings have been revised. (Note: Trade names start with a
capital. Generic names start with a lower case letter.)
| Medication | Classification | Remarks/Cross References |
| abacavir Ziagen |
ANTIRETROVIRAL, NRTI | Refer to HIV book |
| Adderall | ANTI-ADHD, ANTINARCOLEPSY, Stimulant | See dextroamphetamine, amphetamine, amphetamines |
| Allegra-D (SR) | ANTIHISTAMINE, DECONGESTANT | See fexofenadine p & pseudoephedrine p |
| amphetamines | ANTI-ADHD, Stimulant | replace dextroamphetamine |
| Anzemet | ANTIEMETIC | See dolasetron mesylate p |
| Arava | ANTIARTHRITIC (rheumatoid arthritis) | See leflunomide |
| Arthrotec Tab—lactose, corn starch |
NSAID, ANALGESIC, ANTIARTHRITIC and ANTIULCER, Gastric Mucosa Protectant | See diclofenac sodium and see misoprostol |
| Astelin | ANTIHISTAMINE | See azelastine HCl |
| Atacand | ANTIHYPERTENSIVE | See candesartan cilexetil |
| Avandia | ANTI-DIABETIC | See rosigilitazone maleate |
| Avapro | ANTIHYPERTENSIVE, Angiotensin II Receptor Antagonist | See irbesartan p |
| azelastine
HCl Astelin |
ANTIHISTAMINE | Nasal Spray |
| Baycol | ANTIHYPERLIPIDEMIC, HMG CoA Reductase Inhibitor | See cerivastatin |
| calcium carbonate | Change info: Take a few minutes before meals to ― phosphate binding. Ref: Janssen, MJA et al, 1996 Clin Nephrology 45(2):111-119 | |
| candesartan
cilexetil Atacand |
ANTIHYPERTENSIVE, Angiotensin II Receptor Antagonist | |
| capecitabine Xeloda |
ANTINEOPLASTIC for metastatic breast cancer | Metabolized to 5-FU |
| Carbatrol (extended release capsule) brand of carbamazepine | ||
| carbamazepine | Add Grapefruit Juice interaction | |
| carvedilol Coreg |
ANTI-CHF, ANTIHYPERTENSIVE, Non-selective Beta-Blocker and Alpha1 Blocker | |
| cefdinir Omnicef |
ANTIBIOTIC, Cephalosporin (oral) | |
| Celexa | ANTIDEPRESSANT | See citalopram HBr |
| Celebrex | ANTIARTHRITIC, COX-2 Inhibitor | See celecoxib |
| celecoxib Celebrex |
ANTIARTHRITIC, COX-2 Inhibitor | |
| Cenestin | CONJUGATED ESTROGEN | See estrogen |
| cerivastatin Baycol |
ANTIHYPERLIPIDEMIC, HMG CoA Reductase Inhibitor | |
| chlorzoxazone | Add watercress interaction | |
| cilostazol Pletal |
Phosphodiesterase III Inhibitor Platelet aggregation Inhibitor | REDUCTION OF SYMPTOMS OF INTERMITTENT CLAUDICATION |
| citalopram
HBr Celexa |
ANTIDEPRESSANT | |
| Coreg | ANTI-CHF, ANTIHYPERTENSIVE, Non-selective Beta-Blocker | See carvedilol |
| delavirdine
mesylate Rescriptor |
ANTIRETROVIRAL | refer to HIV book |
| Detrol | BLADDER CONTROL AGENT, muscarinic receptor antagonist | See tolterodine tartrate |
| diazepam | ADD GJ interaction | |
| dolasetron
mesylate Anzemet |
Antiemetic | |
| efavirenz Sustiva |
ANTIRETROVIRAL | refer to HIV book |
| Enbrel | ANTI-ARTHRITIC | See etanercept p |
| Endocet | ANALGESIC, Narcotic | See oxycodone p & acetaminophen p |
| etanercept Enbrel |
ANTI-ARTHRITIC (rheumatoid arthritis) | |
| Evista | ANTI-OSTEOPOROSIS, SERM | See raloxifene p |
| Fareston | ANTINEOPLASTIC (breast cancer) | See toremifene citrate |
| Femara | ANTINEOPLASTIC (breast cancer), Aromatase Inhibitor | See letrozole |
| fenofibrate Tricor |
ANTIHYPERLIPIDEMIC | |
| fluvastatin | new indication to ¯ TG & apolipoprotein B, also ¯ frequency of LFT’s | |
| Gabitril | ANTICONVULSANT | See tiagabine HCl |
| gingko biloba | Herbal Product | |
| ginseng | Herbal Product | |
| glimepiride | new indication with metformin | |
| Glyset | ORAL HYPOGLYCEMIC | See miglitol |
| interferon
alfacon-1 Infergen |
synthetic interferon for hepatitis C | Refer to interferon alfa |
| irbesartan Avapro |
ANTIHYPERTENSIVE, Angiotension II Receptor Antagonist | |
| leflunomide Arava |
ANTIARTHRITIC (rheumatoid arthritis) | |
| letrozole Femara |
ANTINEOPLASTIC (breast cancer), Aromatase Inhibitor | |
| levofloxacin Levaquin |
ANTIBIOTIC, Fluoroquinolone | See listing for ofloxacin |
| lovastatin | Add GJ interaction. Add to slow progression of CHD. | |
| melatonin | HORMONE, Natural Product, used as SLEEP AIDE | |
| Meridia | APPETITE SUPPRESANT | See sibutramine |
| Micardis | ANTIHYPERTENSIVE | See telmisartan |
| miglitol Glyset |
ORAL HYPOGLYCEMIC | |
| Mirapex | ANTIPARKINSON, Dopamine Agonist | See pramipexole |
| oprelvekin Neumega |
PLATELET GROWTH FACTOR (to prevent thrombocytopenia) | |
| orlistat Xenical |
WEIGHT CONTROL AGENT, Lipase Inhibitor | |
| oxybuynin Cl | Add Ditropan XL | |
| paroxetine | Add ANTI SOCIAL ANXIETY | |
| Pletal | REDUCTION OF SYMPTOMS OF INTERMITTENT CLAUDICATION. | See cilostazol |
| pramipexole Mirapex |
ANTIPARKINSON, Dopamine Agonist | |
| Prandin | ORAL HYPOGLYCEMIC, Meglitinide | See repaglinide |
| Prevpac | ANTI-ULCER combo: prevacid, biaxin, amoxicillin for H. P ylori | |
| progesterone Prometrium |
HORMONE | |
| Propecia | Treatment of male pattern baldness | See finasteride |
| quetiapine
fumarate Seroquel |
ANTIPSYCHOTIC |
|
| raloxifene Evista |
ANTI-OSTEOPOROSIS, Selective Estrogen Receptor Modulator (SERM) | |
| Ranagel | PHOSPHATE BINDER (for use in ESRD) | See sevelamar HCl |
| repaglinide Prandin |
ORAL HYPOGLYCEMIC, Meglitinide | |
| Requip | ANTIPARKINSON, Dopamine agonist | See ropinirole HCl |
| rituximab Rituxan |
ANTINEOPLASTIC, Monoclonal Antibody for non-Hodgkin’s lymphoma | |
| rizatriptan Maxalt |
ANTIMIGRAINE | See listing for sumatriptan succinate |
| rofecoxib Vioxx |
ANTIARTHRITIC, COX-2 Inhibitor | |
| ropinirole
HCl Requip |
ANTIPARKINSON, Dopamine agonist | |
| St. John’s Wort | Herbal Product | |
| saw palmetto | Herbal Product | |
| Seroquel | ANTIPSYCHOTIC | See quetiapine fumarate |
| sevelamar
HCl Ranagel |
PHOSPHATE BINDER (for use in ESRD) | |
| sibutramine Meridia |
APPETITE SUPPRESANT | |
| simvastatin | Add GJ interaction | |
| singulair | ANTI ASTHMA | See montelukast |
| telmisartan Micardis |
ANTIHYPERTENSIVE, angiotensin II receptor blocker | See listing for losartan |
| theophylline | ADD Pyr —reduction of CNS effects. Bartel, PR et al Am J Clin Nutr 1994;60: 93-99 paper. | |
| tiagabine
HCl Gabitril |
ANTICONVULSANT | |
| ticlopidine HCl | (note new warning 1999) | |
| tolterodine
tartrate Detrol |
BLADDER CONTROL AGENT | |
| TOBI brand of tobramycin | ANTIBIOTIC | Oral Inhalant |
| topiramate Topamax |
ANTICONVULSANT | |
| toremifene
citrate Fareston |
ANTINEOPLASTIC (breast cancer), Estrogen Antagonist | See listing for tamoxifen |
| Tricor | ANTIHYPERLIPIDEMIC | See fenofibrate |
| Viactiv | CALCIUM SUPPLEMENT | See calcium carbonate |
| Vioxx | ANTIARTHRITIC, COX-2 Inhibitor | See rofecoxib |
| Xeloda | ANTINEOPLASTIC for metastatic breast cancer | See capecitabine |
| Xenical | WEIGHT CONTROL AGENT | See orlistat |
| Ziagen | ANTIRETROVIRAL, NRTI | See abacavir. Refer to HIV book |
| zileutron Zyflo |
ANTIASTHMA | |
| Zithromax IV | brand of IV azithromycin | |
| Zyflo | ANTIASTHMA | See zileutron |
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