oxandrolone |
ANTIWASTING,
Anabolic Steroid |
Oxandrin
Tab- cornstarch,
lactose |
To promote wt gain after surgery, trauma, infection
To ¯
bone pain in osteoporosis. To offset Pro catabolism with
corticosteroids.
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|
Diet:
Requires adequate cal & pro intake for anabolic effect.
Possibly ¯
Na.
Nutr:
appetite,
wt,
lean
body mass,
protein
synthesis.
Oral/GI: N/V, diarrhea.
S/Cond: Not with lactation. 94-97% serum pro
bound.12
Not with severe hepatic dysfunction, hypercalcemia, breast
cancer,
nephrosis, prostatic cancer or hypertrophy.
Caution with CAD or diabeticson insulin/oral hypoglycemics-
¯
glucose.
Caution with ¯
renal or ¯
hepatic func.12
Pregnancy: Category X.
Other: Acne, virilism in females/prepubertal
males, menstrual or
testicular changes, excitation, insomnia, peripheral edema,
chills,
muscle cramps, depression, jaundice, skin discoloration.
Hypercalcemia
in females.
Rare, but may be fatal, peliosis hepatis, hepatocellular
tumor.
Blood/Serum:
CPK,
chol,
LDL, ¯
HDL,
crea,
PT,
¯
clotting factors,
glucose,
Ca,
P,
K,
Na,
Cl,
bil,
AST,
ALT,
alk phos, ¯ LH,
¯ FSH.
Urinary:
crea. Bladder irritability.
Monitor: Glucose in diabetics. Lipid panel. Hepatic
func.
Hb/HCT with high dose. Wt. Bone growth in children with LT
use.. |
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|
oxaprozin
Daypro |
NSAID,
ANTIARTHRITIC See listing for ibuprofen p 166
Tab- starch |
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